Psoriasis (PsO) is a common, chronic, systemic, inflammatory disease that begins in the immune system.1-3 It affects the skin, with regular symptoms of pain, itch, and bleeding reported by patients.

The prevalence of PsO is about 2% in North America and Europe, and it increases with age, affecting both men and women equally.

While most cases of psoriasis are mild and can be treated with topical therapies, 20%–30% of cases cannot be treated with topical therapies.4


Five types of PsO have been reported: plaque, guttate or eruptive, inverse, pustular, and erythrodermic.4 Patients with PsO are at an increased risk of developing comorbid diseases,4 with up to 42% of patients developing psoriatic arthritis.5


There is a complex interplay between cutaneous cells and the immune system that produces the hallmark features of PsO.4


Inflammation Pathways in Psoriasis (PsO)1-7

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